{"id":3127,"date":"2025-05-19T11:48:31","date_gmt":"2025-05-19T09:48:31","guid":{"rendered":"https:\/\/www.ihu-infiny.fr\/non-classifiee\/world-ibd-day-2025-when-research-sheds-light-on-hidden-challenges\/"},"modified":"2025-05-19T13:41:06","modified_gmt":"2025-05-19T11:41:06","slug":"world-ibd-day-2025-when-research-sheds-light-on-hidden-challenges","status":"publish","type":"post","link":"https:\/\/www.ihu-infiny.fr\/en\/news\/world-ibd-day-2025-when-research-sheds-light-on-hidden-challenges\/","title":{"rendered":"World IBD Day 2025: When research sheds light on hidden challenges"},"content":{"rendered":"\n

To mark World IBD Day, IHU Infiny and Afa Crohn RCH co-hosted a scientific conference highlighting two forward-looking research projects, supported by both Afa and IHU Infiny.<\/p>\n\n

The event was opened by Beno\u00eet Chassaing, Fundamental and translational research Director of IHU Infiny, and Anne Buisson, Executive Director of Afa Crohn RCH, who emphasized the importance of aligning research excellence with lived patient experience to advance inflammatory bowel diseases (IBD) care.<\/p>\n\n

Two presentations, two scientific angles, one shared goal: to better understand and IBD.<\/p>\n\n

Microplastics and intestinal inflammation: an emerging link<\/h3>\n\n

Dj\u00e9sia Arnone (Experimental Research at IHU, NGERE \u2013 Inserm, Universit\u00e9 de Lorraine) shared early findings suggesting that chronic exposure to microplastics could worsen intestinal inflammation.The project, conducted with PhD candidate Claire Masi, investigates how different microplastic types affect cell viability, immune responses, and colitis severity in preclinical models. <\/p>\n\n

Why does it matter <\/strong>This topic is still relatively new in human health research. These findings could help us understand how environmental exposure to plastics affects not just IBD patients, but digestive health more broadly, with clear implications for global and environmental health.<\/p>\n\n

IBD and cardiovascular risk: looking beyond the gut<\/h3>\n\n

J\u00e9r\u00e9my Lagrange (CRCN, DCAC \u2013 Inserm, Universit\u00e9 de Lorraine) explored the role of the glycocalyx, a protective endothelial layer that may deteriorate in the inflammatory environment of IBD.His study reveals that such degradation could contribute to a higher risk of thrombosis among patients. <\/p>\n\n

Why does it matter?<\/strong> People living with IBD face a two- to threefold increased risk of thrombotic complications. Understanding this mechanism opens the door to novel biomarkers and improved cardiovascular prevention strategies. <\/p>\n\n

\n\n

High translational potential<\/strong>These projects reflect IHU Infiny\u2019s mission: to connect fundamental, translational, and clinical research, turning new knowledge into concrete benefits for patients.<\/p>\n\n

Special thanks to our partner Afa Crohn RCH<\/strong>, whose 360\u00b0 commitment \u2014 funding research, supporting patients, raising awareness \u2014 makes it a driving force in the IBD ecosystem. These synergies are invaluable and reflect a shared commitment to putting patients at the heart of scientific and medical progress. <\/p>\n\n

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<\/p>\n\n

A second conference will take place on May 19<\/strong> as part of our World IBD Day program.It will focus on the latest advances in IBD management<\/strong> \u2014 from care pathways to innovative treatments.Free registration<\/strong><\/a> <\/p>\n\n

From May 17 to 23<\/strong>, we\u2019ll also be present at several public information booths<\/strong>.Check out our full program<\/strong><\/a> to find out where to meet us and learn more about inflammatory bowel diseases (IBD). <\/p>\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

To mark World IBD Day, IHU Infiny and Afa Crohn RCH co-hosted a scientific conference highlighting two forward-looking research projects, supported by both Afa and IHU Infiny. The event was opened by Beno\u00eet Chassaing, Fundamental and translational research Director of IHU Infiny, and Anne Buisson, Executive Director of Afa Crohn RCH, who emphasized the importance […]<\/p>\n","protected":false},"author":5,"featured_media":3128,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[36],"tags":[41],"class_list":["post-3127","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/posts\/3127","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/comments?post=3127"}],"version-history":[{"count":0,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/posts\/3127\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/media\/3128"}],"wp:attachment":[{"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/media?parent=3127"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/categories?post=3127"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ihu-infiny.fr\/en\/wp-json\/wp\/v2\/tags?post=3127"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}