Recap – Scientific Symposium 2025 #FUTURES

On October 15, IHU Infiny brought together researchers, clinicians and partners in Nancy for the second edition of its scientific symposium FUTURES.

The event was rich in discussion and collaboration around a shared goal: to better understand the gut–brain axis and its links with diet and the environment, in order to advance research and patient care in the field of inflammatory bowel disease (IBD).

Francisca Joly (Beaujon Hospital, AP-HP) opened the day with a clear and engaging presentation on the gut as a “second brain.” She highlighted the diversity of the microbiota and explained how this inner ecosystem influences immunity, metabolism, and even emotions—offering a talk that was both scientific and accessible.

Charles Bernstein (University of Manitoba, Winnipeg, Canada) then explored the often-underestimated issue of chronic fatigue in IBD, linking it to circadian rhythm disruption, stress, and microbiota imbalance.

Bruno Bonaz (CHU Grenoble) presented the promising anti-inflammatory effects of vagus nerve stimulation, while Malvyne Rolli-Derkinderen (TENS, Inserm–University of Nantes) shed light on the role of the enteric nervous system in maintaining intestinal barrier function.

Émilie Viennois (CRI, Inserm–Université Paris Cité) introduced new perspectives on microRNAs and their role in shaping the host–microbiota interface from the earliest stages of life.

The afternoon highlighted the Nancy site’s expertise in imaging and artificial intelligence, with presentations from Valérie Laurent (CHRU de Nancy), Freddy Odille (IADI, Inserm–Université de Lorraine), and teams from IADI, the University of Lorraine, and CIC-IT. Their projects are helping develop more precise and less invasive diagnostic tools, supporting smoother and more personalized patient care pathways.

From molecular biology to clinical application, FUTURES 2025 embodied IHU Infiny’s mission:

  • Investing in research to improve care
  • Integrating nutrition and environment into disease prevention and management
  • Promoting a comprehensive approach to gut health, focused on prevention and precision medicine

These directions place IHU Infiny at the heart of a dynamic ecosystem where science, innovation, and society move forward together to reshape the future of digestive health.

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